Emerging Research on Mesothelioma Cell Types/ Pathways to Innovative Therapies
Classification of Mesothelioma Cell Types
Mesothelioma, a malignancy linked to asbestos exposure, presents a complex challenge due to its diverse cellular makeup. Researchers have identified three primary cell types that characterize the disease: epithelioid, sarcomatoid, and biphasic, each with distinct histological and clinical features.
Epithelioid mesothelioma is the most common and exhibits cells that are relatively uniform in shape with a tubular pattern. This type is associated with a better prognosis and a more favorable response to treatment.
Sarcomatoid mesothelioma is characterized by spindle-shaped cells and a more aggressive behavior, often leading to a poorer prognosis. Due to its resilience, it poses significant challenges in treatment.
Biphasic mesothelioma cont...